What are the Clinical Implications of CD8 T Cells?

CD8 T cells are a focal point in many clinical settings. Their levels and functionality can be indicative of the body's ability to fight infections and cancer. In immunotherapy, strategies like CAR-T cell therapy aim to enhance the activity of CD8 T cells against tumors. Conversely, in autoimmune diseases, the activity of CD8 T cells may be dysregulated, leading to tissue damage. Understanding the histological aspects of CD8 T cells can thus provide critical insights for diagnostics and therapeutic interventions.