Understanding VEGF has led to significant clinical applications. Anti-VEGF drugs, such as bevacizumab (Avastin), are used to treat various cancers by inhibiting blood vessel formation. VEGF inhibitors are also used in ophthalmology to treat conditions like wet macular degeneration. Conversely, VEGF is used in therapeutic angiogenesis, where it is administered to promote blood vessel growth in ischemic tissues, such as in peripheral artery disease.
