Here are the details of each layer of the entorhinal cortex:
Layer I: This superficial layer contains relatively few neurons and is primarily composed of dendrites from deeper neurons, as well as a rich network of axons and glial cells. Layer II: Characterized by densely packed stellate cells, this layer is crucial for receiving input from the neocortex and transmitting it to the hippocampus. Layer III: Composed mainly of pyramidal neurons, Layer III sends projections to the CA1 region of the hippocampus and the subiculum. Layer IV: This layer is less distinct in the entorhinal cortex and is often referred to as the lamina dissecans. It serves as a transitional zone between the superficial and deep layers. Layer V: Contains large pyramidal cells that project to the deep layers of the neocortex and subcortical structures. Layer VI: This deepest layer features a mix of different cell types and projects to the thalamus and other subcortical regions.
