Researchers study type II pneumocytes using various histological techniques, including light microscopy, electron microscopy, and immunohistochemistry. Specific markers such as surfactant proteins (e.g., SP-A, SP-B, SP-C) are used to identify and characterize these cells. In addition, cell culture models and animal studies are employed to investigate the function and behavior of type II pneumocytes under different physiological and pathological conditions.
