What are the Challenges in Working with Histological Samples?
Several challenges can arise when working with histological samples: 1. Artifact Formation: Improper handling or preparation can introduce artifacts that may obscure or mimic pathological findings. 2. Tissue Preservation: Ensuring that samples are properly fixed and stored to prevent degradation over time. 3. Sample Size: Obtaining a sufficiently large and representative sample can be difficult, particularly in needle biopsies. 4. Interpreting Results: Variability in staining and tissue architecture can make interpretation challenging, requiring expertise and experience.