What are the Challenges in Using Diagnostic Markers?
While diagnostic markers are invaluable, there are several challenges associated with their use:
Specificity: Some markers may not be entirely specific to a particular disease, leading to false positives. Sensitivity: Low levels of a marker in tissue samples can lead to false negatives. Technical Variability: Differences in tissue processing, staining, and interpretation can affect the accuracy of marker detection. Cost and Accessibility: Advanced techniques for detecting markers can be expensive and may not be available in all laboratories.
