Despite its potential, therapeutic targeting faces several challenges: - Heterogeneity of Diseases: Diseases like cancer can have significant variability between patients, making it difficult to identify universal targets. - Off-Target Effects: Drugs may interact with non-target molecules, leading to side effects. - Resistance Development: Targets can evolve, rendering therapies less effective over time. - Delivery Issues: Effectively delivering the therapeutic agent to the target tissue without degradation or loss of function.
