What Are the Challenges in Analyzing Nucleic Acid Sequences in Histology?
Analyzing nucleic acid sequences in histological samples presents several challenges:
1. Sample Preservation: Ensuring that tissue samples are well-preserved is crucial for accurate nucleic acid analysis. Degradation of DNA or RNA can lead to erroneous results. 2. Technical Complexity: Techniques like NGS and ISH require sophisticated equipment and expertise, which may not be available in all laboratories. 3. Interpretation of Data: The vast amount of data generated, especially by NGS, necessitates advanced bioinformatics tools for proper interpretation. This can be a bottleneck in translating raw data into actionable insights.
