What Are the Challenges Associated with Cell Culture Collections?
Despite their benefits, cell culture collections face several challenges:
Contamination: Ensuring cell lines are free from microbial and cross-contamination remains a significant concern. Genetic Drift: Prolonged culture can lead to genetic changes in cell lines, affecting their reliability. Ethical Considerations: The use of human and animal cell lines involves ethical considerations that must be addressed. Cost: Maintaining and distributing cell lines can be expensive, potentially limiting access for some researchers.