What are the Applications of Single Cell DNase-seq?
Single cell DNase-seq has a broad range of applications:
1. Cancer Research: By examining tumor samples at single-cell resolution, researchers can identify subpopulations of cancer cells with distinct regulatory landscapes, potentially leading to more targeted therapies.
2. Neuroscience: In the study of brain tissues, this technique helps map the regulatory elements associated with different neuronal types and states, aiding in the understanding of brain function and disorders.
3. Immunology: Single cell DNase-seq can be used to profile immune cells, revealing how chromatin accessibility changes in response to infections or during immune cell differentiation.
