Using carbon 13 in histological studies has several advantages: - Non-Radioactive: Unlike some other isotopes, carbon 13 is stable and non-radioactive, making it safer for use in biological studies. - High Sensitivity: The slight difference in mass between carbon 12 and carbon 13 allows for high sensitivity in detection techniques. - Metabolic Insights: Carbon 13 labeling provides detailed insights into metabolic pathways, enabling a better understanding of cellular processes and disease mechanisms.