What are Sterol Regulatory Element Binding Proteins (SREBPs)?
Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors that play a critical role in lipid homeostasis. These proteins regulate the synthesis of cholesterol, fatty acids, and triglycerides. SREBPs are encoded by the SREBF1 and SREBF2 genes and are synthesized as inactive precursors bound to the endoplasmic reticulum (ER) membrane.
