There are over 60 different Rab GTPases in humans, each with specific roles. For instance, Rab5 is involved in early endosome fusion, while Rab7 regulates late endosome maturation. Rab11 is essential for recycling endosomes back to the plasma membrane, and Rab1 plays a critical role in vesicle transport between the endoplasmic reticulum and Golgi apparatus.