What Are Some Examples of Metabolic Disorders Studied Through Histology?

Several metabolic disorders have been extensively studied using histological techniques. Some prominent examples include:

Diabetes Mellitus: Histological analysis of pancreatic tissues can reveal the loss of insulin-producing beta cells or the presence of amyloid deposits.
Non-Alcoholic Fatty Liver Disease (NAFLD): Liver biopsies stained with Oil Red O can show the extent of lipid accumulation and possible progression to non-alcoholic steatohepatitis (NASH).
Glycogen Storage Diseases: PAS staining of liver or muscle tissues can illustrate abnormal glycogen accumulation.
Lysosomal Storage Diseases: Histological examination can reveal vacuolation in cells due to the accumulation of undigested substrates.