What Are Some Disorders Related to Defective Attachment?
Defects in cellular attachment can lead to various health issues:
Epidermolysis Bullosa: A group of genetic disorders characterized by fragile skin due to defective anchoring between the epidermis and dermis. Cancer Metastasis: Abnormal cell adhesion can facilitate the detachment and spread of cancer cells from the primary tumor to distant sites. Cardiomyopathy: Mutations affecting desmosomal proteins can weaken heart muscle cells, leading to conditions like arrhythmogenic right ventricular cardiomyopathy.