What are Some Diseases Associated with Vesicle Fusion Defects?
Defects in vesicle fusion can lead to a variety of diseases. For example, mutations in SNARE proteins are linked to neurodegenerative diseases such as Alzheimer's and Parkinson's. Impaired vesicle fusion can also result in endocrine disorders, as seen in certain types of diabetes and congenital adrenal hyperplasia. Understanding the mechanics of vesicle fusion is therefore crucial for developing therapeutic strategies for these conditions.