What are Some Diseases Associated with Microfilament Dysfunction?
Defects in microfilament function or regulation can lead to various diseases, including:
Muscular Dystrophies: Mutations affecting actin or related proteins can cause muscular dystrophies. Cancer: Abnormal actin dynamics are often found in cancer cells, aiding in their ability to migrate and invade tissues. Neurodegenerative Diseases: Dysfunctional actin can lead to problems in neuronal transport and cell death, contributing to diseases like Alzheimer's and Parkinson's.