Rag GTPases are a family of small GTP-binding proteins that play a crucial role in cellular metabolism, particularly in the mTOR (mechanistic target of rapamycin) signaling pathway. These proteins are essential for the regulation of cell growth, proliferation, and autophagy. The Rag GTPases consist of four members: RagA, RagB, RagC, and RagD, which form heterodimers (RagA/B with RagC/D) to function effectively.