Several disorders can affect neutrophils, leading to either an increased or decreased number in the blood: - Neutrophilia: An increase in neutrophil count, often in response to infection, inflammation, or stress. - Neutropenia: A decrease in neutrophil count, which can be caused by conditions such as bone marrow disorders, chemotherapy, or severe infections. Neutropenia increases the risk of infections. - Chronic Granulomatous Disease (CGD): A genetic disorder affecting the oxidative burst in neutrophils, leading to recurrent infections.
