The process of neutrophil migration involves a series of steps: 1. Chemotaxis: Neutrophils are attracted to infection sites by chemotactic factors such as interleukin-8 (IL-8) and formyl peptides. 2. Adhesion: Neutrophils adhere to the endothelium of blood vessels through interactions with adhesion molecules like selectins and integrins. 3. Diapedesis: Neutrophils move through the endothelial cell layer into the tissue, a process known as diapedesis or transmigration.
