In histology, several markers are crucial for prognosis:
1. Tumor Grade: Indicates how much tumor cells differ from normal cells. Higher grades often correlate with more aggressive cancers. 2. Tumor Stage: Refers to the extent of the tumor's spread in the body. Staging often involves the size of the tumor, lymph node involvement, and presence of metastasis. 3. Mitotic Index: Measures how many cells are dividing. A high mitotic index suggests rapid growth and a poorer prognosis. 4. Necrosis: The presence of dead cells within a tumor can indicate a more aggressive disease. 5. Angiogenesis: The formation of new blood vessels within a tumor, which can supply nutrients and allow it to grow and spread.
