Janus Kinase (Jak) inhibitors, often referred to as Jakinibs, represent a class of medications that target the Janus kinase family of enzymes. These enzymes play a significant role in the signaling pathways of various cytokines and growth factors involved in hematopoiesis and immune function. By inhibiting these enzymes, Jak inhibitors can modulate the immune response, making them valuable in the treatment of various autoimmune diseases and cancers.