guanine nucleotide exchange factors (gefs)

What are Guanine Nucleotide Exchange Factors (GEFs)?

Guanine Nucleotide Exchange Factors (GEFs) are proteins that activate small GTPases by stimulating the release of GDP to allow binding of GTP. This activation process is critical for the regulation of various cellular processes, including cell growth, cytoskeletal rearrangements, and vesicular trafficking.

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