Several issues can arise due to incorrect brightness settings: 1. Overexposure: Excessive brightness can lead to overexposed images, where details are lost in areas that appear too bright or washed out. 2. Underexposure: Insufficient brightness can result in underexposed images, where details are obscured in darkened areas. 3. Glare: Intense localized brightness can cause glare, making it difficult to observe certain regions of the tissue.