What are Common Metabolic Disorders Observed in Histology?
Common metabolic disorders that can be diagnosed histologically include:
Diabetes Mellitus: Characterized by changes in the renal glomeruli, pancreatic islets, and peripheral nerves. Fatty Liver Disease: Marked by lipid accumulation in hepatocytes. Glycogen Storage Diseases: Where excessive glycogen is stored in cells, altering their normal appearance. Lysosomal Storage Disorders: Such as Gaucher's disease, where specific enzymes are deficient, leading to substrate accumulation in lysosomes. Hyperlipidemia: Often showing lipid-laden macrophages in various tissues.
