Several disorders involve melanocytes, the most notable being vitiligo and melanoma. In vitiligo, melanocytes are destroyed, leading to depigmented patches on the skin. Melanoma is a type of skin cancer originating from melanocytes and is characterized by the uncontrolled growth of these pigment-producing cells. Other conditions include albinism, where there is a genetic defect in melanin production, leading to little or no pigment in the skin, hair, and eyes.