1. Proper Slide Preparation: Ensure slides are clean and appropriately coated. Use positively charged or adhesive-coated slides for better results. 2. Optimal Tissue Processing: Follow standardized protocols for tissue fixation and embedding to maintain tissue integrity. 3. Use of Appropriate Adhesives: Select adhesives that are compatible with the tissue type and staining methods. 4. Environmental Control: Maintain consistent environmental conditions to minimize the impact of humidity and temperature on adhesive properties.