Histological techniques are invaluable for studying tumor cell migration. Tissue sections stained with hematoxylin and eosin (H&E) can reveal the architecture of tumors and surrounding tissues. Immunohistochemistry (IHC) allows for the visualization of specific proteins related to migration, such as MMPs or integrins. Additionally, in situ hybridization can be employed to detect mRNA expression levels of genes involved in migration.