The Metavir Score is determined through the histological examination of a liver biopsy sample. This process involves:
Liver Biopsy: A small sample of liver tissue is obtained using a needle. Histological Staining: The tissue sample is stained using specific dyes to highlight the structures and cellular components. Microscopic Examination: A pathologist examines the stained tissue under a microscope to assess the degree of fibrosis and inflammation.