How is Programmed Cell Death Studied in Histology?
In histology, programmed cell death is studied using various techniques. TUNEL assay is commonly used to detect DNA fragmentation, a hallmark of apoptosis. Immunohistochemistry can be employed to identify specific markers of apoptosis, autophagy, or necroptosis. Electron microscopy provides detailed images of the morphological changes associated with different forms of cell death.