How Is PKU Managed and Its Histological Impact Mitigated?
Early diagnosis and management of PKU are crucial to prevent its histological and neurological impact. The primary treatment is a low-phenylalanine diet, which minimizes the intake of phenylalanine and prevents its accumulation in the blood. This dietary intervention is most effective when started early in life, ideally shortly after birth. With proper management, the histological abnormalities associated with PKU can be minimized, allowing for normal brain development and function.
