Biopsy: A sample of tissue is removed from the patient. Fixation: The tissue is preserved using chemicals like formalin to prevent decay. Embedding: The tissue is embedded in a solid medium, usually paraffin wax, to allow for thin slicing. Sectioning: The tissue is sliced into very thin sections using a microtome. Staining: Various stains, such as Hematoxylin and Eosin (H&E), are applied to highlight different cellular components. Microscopic Examination: The stained tissue sections are examined under a microscope to identify pathological changes.