Interpreting PAS-stained sections requires a good understanding of tissue morphology and staining characteristics. Pathologists look for the presence and distribution of the magenta or purple coloration to identify areas rich in polysaccharides or mucin. They also assess the pattern and intensity of staining to make a diagnosis. For instance, a diffuse PAS-positive staining in the liver may indicate glycogen storage disease, while focal PAS-positive staining in a kidney biopsy could suggest glomerular basement membrane thickening.
