In histological studies, osteocalcin is often used as a marker for bone formation. Researchers use immunohistochemistry techniques to detect and visualize osteocalcin in bone tissue sections. This helps in studying the activity of osteoblasts and the process of bone remodeling. Additionally, osteocalcin is used in cell culture studies to assess the osteogenic potential of various treatments or interventions aimed at enhancing bone regeneration.
