How is Muscular Dystrophy Diagnosed Histologically?
The diagnosis of MD often involves the examination of muscle biopsies under a microscope. Specific staining techniques such as Hematoxylin and Eosin (H&E) staining are used to observe muscle fiber structure, while immunohistochemical staining can detect the presence or absence of specific muscle proteins like dystrophin. Genetic testing further aids in the diagnosis by identifying mutations in genes associated with different types of MD.