Diagnosing loss of tissue integrity involves several techniques:
Microscopic Examination: Using light or electron microscopy to observe structural changes in tissues. Histochemical Staining: Special stains (e.g., Hematoxylin and Eosin) to highlight specific tissue components and abnormalities. Immunohistochemistry: Using antibodies to detect specific proteins that may indicate tissue damage or disease. Molecular Techniques: PCR, in situ hybridization, and other methods to detect genetic and molecular changes.
