How is Lemierre's Syndrome diagnosed histologically?
While clinical presentation and imaging studies are crucial for diagnosis, histological examination can provide definitive evidence of the syndrome. Biopsies from affected tissues such as the pharyngeal area, lung, or liver can be examined under a microscope. Key histological features include: - Presence of Fusobacterium necrophorum: Identified using special staining techniques like Gram staining. - Acute inflammation: Neutrophilic infiltration, edema, and necrosis. - Thrombus formation: Observed in the internal jugular vein or other affected blood vessels.
