Karyotyping involves several steps: - Cell Culture: Cells are cultured to increase their number. - Arresting Cells: Cells are treated with a chemical like colchicine to arrest them in metaphase. - Harvesting: Cells are harvested and then treated to swell the nuclei for better visualization. - Staining: Chromosomes are stained using dyes like Giemsa. - Analysis: Chromosomes are analyzed under a microscope and arranged in a standard karyotype format.