How is Immunohistochemistry Used in Diagnosing Lymphoma?
Immunohistochemistry (IHC) is pivotal in the diagnosis and classification of lymphoma. Specific markers are used to identify the origin and subtype of the lymphoma. For example, CD20 is a marker for B-cell lymphomas, while CD3 is used for T-cell lymphomas. Reed-Sternberg cells in Hodgkin Lymphoma typically express CD30 and CD15.