Histologists use various techniques to study GroEL, including immunohistochemistry and Western blotting. Immunohistochemistry involves using antibodies specific to GroEL to visualize its localization within tissue samples. Western blotting, on the other hand, allows for the detection and quantification of GroEL in cell or tissue extracts. Additionally, advanced imaging techniques such as electron microscopy can be used to observe the structure of the GroEL-GroES complex at a molecular level.