genetic instability

How is Genetic Instability Detected in Histology?

Histologists can detect genetic instability using various techniques. Immunohistochemistry (IHC) allows for the visualization of specific proteins that may indicate DNA damage or repair mechanisms. Fluorescence in situ hybridization (FISH) is employed to identify chromosomal abnormalities. Advanced methods like next-generation sequencing (NGS) and comparative genomic hybridization (CGH) are also used to analyze genetic changes at a high resolution.

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