How is Cholera Toxin B Used in Histological Studies?
CTB is often conjugated with a fluorescent dye or an enzyme like horseradish peroxidase (HRP) to visualize the pathways it traces. This conjugation allows researchers to follow the transport of CTB through neurons, mapping connections and understanding the organization of neuronal networks. CTB's ability to cross synapses makes it particularly useful for studying synaptic connectivity.