How has the use of advanced staining techniques evolved?
Advanced staining techniques, such as fluorescent in situ hybridization (FISH) and chromogenic in situ hybridization (CISH), have greatly enhanced the visualization of specific DNA or RNA sequences within tissues. These techniques are used to detect genetic abnormalities, such as gene amplifications or translocations, which are critical for the diagnosis and treatment of various diseases. They offer high specificity and sensitivity in detecting molecular alterations.
