1. Action Potential Arrival: A nerve impulse travels down the motor neuron to the axon terminal. 2. ACh Release: The action potential triggers the release of ACh into the synaptic cleft. 3. Receptor Binding: ACh binds to nAChRs on the motor end plate, causing ion channels to open. 4. Muscle Depolarization: Sodium ions flow into the muscle fiber, leading to depolarization. 5. Muscle Contraction: The depolarization triggers an action potential in the muscle fiber, leading to contraction.
