SCF functions by binding to the c-Kit receptor (CD117), which is a type of tyrosine kinase receptor found on the surface of HSCs. This interaction triggers a series of intracellular signaling cascades that promote cell survival, proliferation, and differentiation. The binding of SCF to c-Kit initiates pathways such as the PI3K/Akt and MAPK/ERK pathways, which are critical for cell growth and survival.
