Renal damage can manifest in various ways depending on the underlying cause. Common histological signs include glomerulosclerosis (scarring of the glomeruli), tubular atrophy (wasting away of the tubules), and interstitial fibrosis (accumulation of fibrous tissue in the interstitial space). Inflammatory cells may infiltrate the renal tissue, and there may be evidence of necrosis or apoptosis (cell death).
