How Does RANKL Interact with Osteoprotegerin (OPG)?
Osteoprotegerin (OPG) is a decoy receptor that binds to RANKL, preventing it from interacting with RANK. By inhibiting the RANKL-RANK interaction, OPG plays a protective role against excessive bone resorption. The RANKL/OPG ratio is a key factor in controlling bone density and health.
