cellular signaling pathways

How Do Cellular Signaling Pathways Work?

Cellular signaling pathways typically follow a series of steps:
Signal Reception: A ligand binds to its specific receptor on the cell surface or inside the cell.
Signal Transduction: The receptor undergoes a conformational change, activating intracellular signaling molecules and second messengers.
Signal Amplification: The signal is amplified through a cascade of enzymatic reactions, often involving kinases and phosphatases.
Cellular Response: The amplified signal leads to a specific cellular response, such as gene expression, changes in cell metabolism, or alteration of cell shape.
Signal Termination: The pathway is turned off to reset the system, ensuring the cell can respond to new signals.

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