How does NRF1 interact with other cellular pathways?
NRF1 interacts with several cellular pathways to coordinate energy metabolism and cellular homeostasis. It works in conjunction with other transcription factors such as NRF2 and PGC-1α, forming a network that regulates the expression of genes involved in oxidative stress response, mitochondrial biogenesis, and lipid metabolism. This interplay is crucial for adapting to changes in cellular energy demands and environmental conditions.
