The mutational status of a tumor can significantly influence treatment decisions. For example:
Targeted Therapy: Drugs can be designed to specifically target mutated proteins. For instance, BRAF inhibitors are used to treat melanomas with BRAF mutations. Immunotherapy: Some mutations affect the immune environment of tumors, making them more or less responsive to immunotherapy. Chemotherapy Resistance: Certain mutations can confer resistance to standard chemotherapy, necessitating alternative treatments.